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Bactrim Information
What is Bactrim recommended for?
We can make plans for future, long for something and be aware of thousands of different dangers and obstacles around us, but there are always billions of vicious threats around us that we cannot escape from - bacteria. They are invisible because they are too tiny to be discerned without a microscope but the harm they cause is so big that people can suffer for weeks and their body will not be able to defeat the problem. Only their doctor can find the best way out and prescribe a highly effective medication like Bactrim for handling their health disorder.
Bactrim is a reliable synthetic antibacterial combination medication available in tablets. Each tablet contains either 800 mg sulfamethoxazole and 160 mg trimethoprim; or 400 mg sulfamethoxazole and 80 mg trimethoprim for oral administration. Please, bear in mind that Bactrim also contains inactive ingredients such as docusate sodium 85%, sodium benzoate 15%, sodium starch glycolate, magnesium stearate and pregelatinized starch. If you are allergic to any component, please, inform your doctor about this fact before you start Bactrim therapy!
The most important thing about taking Bactrim is using the medication only to treat or prevent infections that are 100% or almost certainly are caused by bacteria. If laboratory testing is not available, local epidemiology may prompt empiric selection of Bactrim therapy.
Medical indications for taking Bactrim
- urinary tract infections caused by Escherichia coli, Klebsiellaspecies, Enterobacter species, Morganella morganii, Proteus mirabilis andProteus vulgaris. Bactrim is perfect at curing uncomplicated urinary tract infections and you seldom need additional medications to get well;
- acute otitis media caused by Streptococcus pneumoniae or Haemophilus influenzae in pediatric patients. Bactrim as a combination of sulfamethoxazole and trimethoprim offers great advantage over many other antimicrobial tablets. Warning: Bactrim must not be prescribed to pediatric patients under two years of age!
- acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae or Haemophilus influenzae in adults. Two components of Bactrim prove to be highly efficient.
- enteritis caused by Shigella flexneri and Shigella sonnei. Bactrim shows positive changes within a few days;
- pneumonia caused by Pneumocystis carinii in individuals who are immunosuppressed and considered to be at an increased risk of developing Pneumocystis carinii pneumonia;
- traveler's diarrhea caused by E. coli.
Bactrim dosage and peculiarities of administration
In adult patients experiencing urinary tract infections and Shigellosis Bactim is usually scheduled as follows: 1 double strength tablet of Bactrim (800 mg sulfamethoxazole and 160 mg trimethoprim) or 2 standard tablets of Bactrim (400 mg sulfamethoxazole and 80 mg trimethoprim) every 12 hours for 10-14 days for Urinary Tract Infections patients and for 5 days in the treatment of shigellosis.
In pediatric patients experiencing Shigellosis and Acute Otitis Media the recommended Bactrim dose is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours. This amount of Bactrim should be given in two divided doses every 12 hours for 10 days for urinary tract infections patients and for 5 days in the treatment of shigellosis. Warning! Bactrim is not the best option for pediatric patients less than 2 months of age!
In adult patients experiencing acute exacerbations of chronic bronchitis the recommended Bactrim dose is 1 double strength tablet of Bactrim (800 mg sulfamethoxazole and 160 mg trimethoprim) or 2 standard tablets of Bactrim (400 mg sulfamethoxazole and 80 mg trimethoprim) every 12 hours for 14 days.
In adult and pediatric patients experiencing Pneumocystis carinii pneumonia the recommended Bactrim dose is 75 to 100 mg/kg sulfamethoxazole and 15 to 20 mg/kg trimethoprim per 24 hours. This amount of Bactrim should be given in equal divided doses every 6 hours for 14-21 days
In prophylaxis adult patients the recommended Bactrim dose is 1 double strength tablet of Bactrim (800 mg sulfamethoxazole and 160 mg trimethoprim) daily on 3 consecutive days per week. In prophylaxis pediatric patients the recommended Bactrim dose is 750 mg/m²/day sulfamethoxazole with 150 mg/m²/day trimethoprim given orally in equally divided doses twice a day on 3 consecutive days per week. Please, remember that the total daily amount of Bactrim should not exceed 1600 mg sulfamethoxazole and 320 mg trimethoprim!
Bactrim reported side effects
As a rule, Bactrim is very well tolerated. The most typical adverse effects of Bactrim are minor gastrointestinal disturbances such as nausea, vomiting, anorexia and allergic skin reactions. Severe side effects such as Stevens-Johnson syndrome, toxic epidermal necrolysis, gulminant hepatic necrisis, agranul ocytosis and aplastic anemia are exceptionally rare. If you never overdose Bactrim and follow your doctor's recommendations you have nothing to worry about!
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