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Celebrex Information
What is Celebrex usually prescribed for?
We can enjoy life and daily activities as long as we are healthy. When people are in pain nothing can distract them or make them happy because their head is full of awful throbbing signals informing that some part of body is in trouble. Occasional pain comes when we get hurt and goes as soon as our wounds are healed. As for chronic pain, it can become a real nightmare for people experiencing it that is why mainstream medicine is always interested and highly effective pain relievers like Celebrex.
Celebrex is a typical sulfa non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis (OA), rheumatoid frthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, painful menstruation and menstrual symptoms and familial adenomatous polyposis (FAP). The majority of Celebrex patients point out considerable relief within an hour.
What is the best way to take Celebrex?
This medication works by reducing hormones that cause inflammation and pain in the body. Celebrex oral capsules contain 50 mg, 100 mg, 200 mg or 400 mg of celecoxib so you can purchase the dosage meeting your personal needs.
Celebrex sould be taken with food or milk to lessen GI reactions. If you have difficulty swallowing capsules, the contents of a Celebrex capsule can be opened and mixed with room temperature applesauce and consumed immediately with water.
Typical Celebrex doses
The recommended doses of Celebrex differ greatly, that is why only your personal doctor can schedule your Celebrex properly.
- OA treatment: the recommended oral dose is 200 mg per day administered as a single dose or as 100 mg twice daily.
- RA treatment: the recommended oral dose is 100 to 200 mg twice daily. JRA requires the dose based on weight (for pediatric patients of 2 years and older). For patients weighting from10 kg to 25 kg the recommended dose is 50 mg twice daily. For patients weighting >25 kg the recommended dose is 100 mg twice daily.
- AS treatment: the recommended dose of Celebrex is 200 mg daily in single or divided doses. If no effect is observed after 6 weeks, a trial of 400 mg daily may be worthwhile.
- Treatment of acute pain and primary dysmenorrhea: the recommended dose of Celebrex is 400 mg initially, followed by an additional 200 mg dose if needed on the first day. Afterwards the recommended dose is 200 mg twice daily as needed.
- Treatment for FAP patients: the recommended oral dose is 400 mg twice per day.
Important information to tell you MD before starting Celebrex
Celebrex requiress caution with some categories of patients. Please, inform your doctor if you are allergic to any foods or drugs or if you have: a history of heart attack, stroke, or blood clot; heart disease, congestive heart failure, high blood pressure; a history of stomach ulcers or bleeding; liver or kidney disease; a seizure disorder such as epilepsy; asthma; polyps in your nose; or a bleeding or blood clotting disorder. Having the details mentioned above your MD will adjust the dose accordingly or will recommend you a safer pain reliever.
Celebrex risks and side effects
Celebrex is a perfect painkiller, but it may cause the risks that increase with duration of use:
- serious gastrointestinal reactions - ulceration, perforation of the stomach or intestines, which can occur without warning symptoms and be fatal.
- GI side effects: nausea, upper abdominal pain, dyspepsia, abdominal pain, vomiting, diarrhea, gastroesophageal reflux and flatulence. Constipation, diverticulitis, dry mouth, dysphagia, eructation, esophagitis, gastritis, gastroenteritis, hemorrhoids, hiatal hernia, melena, stomatitis, tenesmus, tooth disorder, intestinal obstruction, intestinal perforation, colitis with bleeding, esophageal perforation, pancreatitis, cholelithiasis are less common.
- serious cardiovascular events - myocardial infarction and stroke, which can be fatal.
- Cardiovascular side effects: increased blood pressure. Aggravated hypertension, congestive heart failure, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, angina pectoris, coronary artery disorder, myocardial infarction, palpitation, tachycardia and thrombophlebitis are less common.
- Dermatologic side effects: rash, alopecia, dermatitis, nail disorder, photosensitivity reaction, pruritus, erythematous and maculopapular rash, increased sweating, urticaria, cellulitis, dry skin, and skin disorders.
- Endocrine side effects: diabetes mellitus, hypercholesterolemia, and hyperglycemia.
- Hematologic side effects: decreased hematocrit, decreased hemoglobin, and prolonged activated partial thromboplastin time.
- Hepatic side effects: abnormal liver function tests and increased transaminase.
- Renal side effects: increased blood creatinine phosphokinase, increased BUN, and increased creatinine.
- Other side effects: headache, dizziness; cough, upper respiratory tract infection, nasopharyngitis, sinusitis, dyspnea, pharyngitis and rhinitis; somnolence, anorexia, anxiety, increased appetite, depression, nervousness, auditory hallucinations; blurred vision, cataracts, conjunctivitis; arthralgia, arthrosis, bone disorder, hypertonia, leg cramps, myalgia, neck stiffness, synovitis, and tendonitis; proteinuria and hematuria; abnormal urine analysis, bacteriuria; breast neoplasm; increased blood glucose.
Celebrex warnings
- Patients who have an allergic reaction to sulfa and aspirin should not take Celebrex.
- In late pregnancy Celebrex should be avoided.
- Celebrex passes into breast milk and may affect a nursing baby.
- Do not drink alcohol while taking Celebrex - it increases the risk of stomach bleeding.
- Avoid taking Celebrex together with other NSAIDs.
If you take Celebrex for a long period of time, your doctor will check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled appointments!
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