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Generic Diflucan (Fluconazole) Information
Important details about Generic Diflucan (Fluconazole) indications
Fungal infections that affect nails, hair and skin cause much trouble. It is very alarming to hide your hands, wear high boots and boring clothes just because some part of body looks shocking. In addition to purely aesthetic difficulties fungi cause many bothersome symptoms - itching, dryness, peeling etc. The last concern of patients but the major fear of doctors is the fact that fungal infections spread rapidly and cause general damage if the antifungal treatment has not been started in time.
Modern conventional medicine tends to use powerful antifungal antibiotics for managing fungal infections of the mouth, throat, eyes, skin, nails, esophagus, lungs, bladder, genital area, and the blood. Fluconazole is a highly effective antifungal antibiotic that is equally reliable and safe. It is prescribed for curing and preventing different fungi infections including patients with chronic immunity deficiency.
Please, do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Symptoms of a Diflucan overdose may include confusion or unusual thoughts or behavior. Follow the directions on your prescription label carefully to avoid major health risks!
Generic Diflucan (Fluconazole) action and warnings
Fluconazole works by circulating in your blood and destroying fungi. It is known to accumulate in human tissues ensuring a perfect healing effect. If you manage to maintain the necessary amount of Fluconazole in your blood for a period of time long enough for fungi to perish, you will get rid of your infection for good.
Fluconazole is very effective, that is why it interacts with any other medication you might take during your antigungal therapy. You should be very careful and inform your doctor if you have to take:
- a blood thinner such as warfarin (Coumadin);
- clopidogrel (Plavix);
- cyclosporine (Gengraf, Sandimmune, Neoral);
- an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others;
- rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane);
- a sedative such as diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), or midazolam (Versed);
- seizure medication such as phenytoin (Dilantin) or valproic acid (Depakene);
- tacrolimus ((Prograf); or
- theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, etc).
Any other medications can cause Fluconazole dose adjustment. In some cases your MD will recommend you an alternative medication for overcoming fungi.
Patients with sever liver disease, kidney disease, a heart rhythm disorder, a history of Long QT syndrome should be recommended additional tests to make sure Fluconazole is well tolerated and effective.
You should not start Fluconazole therapy if you are allergic to this or similar drugs: clotrimazole (Lotrimin), econazole (Spectazole), ketoconazole (Nizoral), miconazole (Monistat), sertaconazole (Ertaczo), sulconazole (Exelderm), terconazole (Terazol), tioconazole (Vagistat-1), or voriconazole (Vfend).
Patients taking cisapride (Propulsid) or terfenadine (Seldane) should never start using Fluconazole - it is dangerous to take the medications together, you are recommended to have a time span of up to 2 weeks between them!
Fluconazole is a doubtful choice for pregnant and lactating women. It is a FDA pregnancy category C medication; it is hard to say whether Diflucan is harmful to an unborn baby. It is equally undesirable to take Diflucan if you breastfeed a nursing baby. Do not put your child's life to potential danger!
Generic Diflucan (Fluconazole) usual doses
Your Fluconazole dosage depends on the organ affected by fungus and the severity of the process. It is up to your doctor to calculate your personal dose and treatment duration. As a rule, Fluconazole is taken as a single dose once a day in the following quantities:
- Vaginal infections -150 mg of Fluconazole taken only once.
- Nail infections - 150 mg of Fluconazole taken once a week for at least 2-3 months until new healthy nails grow.
- Oropharyngeal candidiasis - 200 mg of Fluconazole on the first day, followed by 100 mg once daily for at least 2 weeks.
- Esophageal candidiasis -200 mg of Fluconazole on the first day; 100 mg once daily for a minimum of three weeks to follow. Sometimes the doses of up to 400 mg/day are used.
- Systemic Candida infections (candidemia, disseminated candidiasis, pneumonia) - doses of up to 400 mg of Fluconazole a day.
- Urinary tract infections and peritonitis - 50-200 mg of Fluconazole daily for a period of time scheduled by your doctor.
- Cryptococcal meningitis - 400 mg of Duflucan on the first day, 200 mg once daily for 10-12 weeks to follow.
- Prophylaxis in patients undergoing bone marrow transplantation - 400 mg of Duflucan once daily.
Generic Diflucan (Fluconazole) side effects
As a rule Fluconazole is well tolerated. Only persons taking high doses of the medication (200 mg of Fluconazole or more daily) for a long period of time (over 2 weeks) risk developing adverse reactions of Fluconazole.
Severe Fluconazole side effects requiring immediate medical help:
- allergy (hives; difficulty breathing; swelling of your face, lips, tongue, or throat);
- GI reactions - nausea, stomach pain, loss of appetite,
- Internal organs reactions - dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes),
- CNS reactions - low fever, fever, chills, body aches, flu symptoms, unusual weakness; seizure (convulsions),
- Skin reactions - severe blistering, peeling, and red skin rash,
- Blood vessels reactions - easy bruising or bleeding,
Minor Fluconazole side effects that do not require medical help:
- mild nausea, vomiting, diarrhea, or upset stomach, unusual or unpleasant taste in your mouth;
- headache; dizziness;
- skin rash or itching.
Other reactions not listed above are possible, too. Inform your doctor about them all and call the ambulance if they persist or become worse.
The best way to avoid Fluconazole side effects is taking the smallest amount of medication possible and using the drug after square meals washing them down with a full glass of water.