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Generic Glucotrol (Glipizide) Information

Generic Glucotrol (Glipizide) indications and action

Number one task of modern medicine is making the life of people with diabetes a perfectly normal one. Glipizide is an oral diabetes medication formulated to control your blood sugar levels. It works by helping your pancreas produce insulin in a normal way. Glucotrol is used with diet and exercise to treat type 2 (non-insulin dependent) diabetes.

Please, read the following information to make sure Glipizide is a proper choice for you and never start taking this medication before you discuss your plans with your healthcare provider!

Generic Glucotrol (Glipizide) doses

Attention! We can speak of general Glipizide dosage, as for you personal Glipizide dose, only your doctor can calculate it in a proper way!

Usual adult Glipizide dose for Diabetes Mellitus Type II is 5 mg (immediate or sustained-release) taken orally once a day, 30 minutes before breakfast for initial dose and 2.5 to 30 mg (immediate-release) orally in 1 or 2 divided doses or 5 to 20 mg (sustained-release) orally in 1 or 2 divided doses for maintained dose.

Usual geriatric Glipizide dose for Diabetes Mellitus Type II is 2.5 to 5 mg taken orally once a day. Doses may be increased in 1 or 2-week intervals in 2.5 to 5 mg/day increments.

It is important to take Glipizide 30 minutes before a meal. If you take Glipizide one time a day, always take it 30 minutes before breakfast. Glipizide XL tablets should be taken with breakfast. Do not crush, chew or break an extended-release Glipizide tablets, swallow them whole. Breaking the pill releases too much drug in your body at one time causing abrupt blood sugar fall.

If you understand you have missed a dose of Glipizide, take the missed dose 30 minutes before your next meal, then return to your regular schedule. Nevertheless, skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose! You may overdose you drug and cause serious health troubles!

Please, remember that Glipizide XL tablets have special shells that are not absorbed in your body, that is why you can see parts of them in your stool. This is a normal thing and you should not worry about this fact, because it will cause you no harm.

Generic Glucotrol (Glipizide) reported side effects

It is a pleasant fact to say that Glipizide is a well-tolerated drug. About one tenth report to have Glipizide adverse reactions but only 1,5% have to discontinue the drug while the rest state that their bothersome symptoms disappear without additional attention. Study the following reactions to make sure your life is out of danger.

Attention! Any allergic reactions to Glipizide: hives; difficulty breathing; swelling of your face, lips, tongue or throat requires emergency medical help! Do not hesitate to cal 911 if you have any signs of Glipizide allergy!

Gastrointestinal side effects are the most common reactions. They are: nausea and diarrhea; constipation and gastralgia, one in one hundred. They appear to be dose related and may disappear on division or reduction of dosage. Cholestatic jaundice may occur rarely with sulfonylureas. Discontinue Glipizide immediately if this occurs.

Dermatologic side effects include allergic skin reactions: erythema, morbilliform or maculopapular eruptions, urticaria, pruritus, and eczema have been reported in about one in seventy patients. These may be transient and may disappear despite continued use of Glipizide; if skin reactions persist, the drug should be discontinued. Porphyria cutanea tarda and photosensitivity reactions have been reported with sulfonylureas.

Hematologic side effects: leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia, aplastic anemia, and pancytopenia have been reported with sulfonylureas.

Metabolic side effects: hepatic porphyria and disulfiram-like reactions have been reported with sulfonylureas. Clinical experience to date has shown that Glipizide has an extremely low incidence of disulfiram-like alcohol reactions.

Endocrine adverse reactions: cases of hyponatremia and the syndrome of inappropriate antidiuretic hormone (SIADH) secretion have been reported with this and other sulfonylureas.

Miscellaneous side effects: dizziness, drowsiness and headache have each been reported in about one in fifty patients treated with Glipizide. They are usually transient and seldom require discontinuance of therapy.

Hepatobiliary side effects: rare cases of cholestatic and hepatocellular forms of liver injury accompanied by jaundice have been reported rarely in association with glipizide. The drug should be discontinued if this occurs.

Generic Glucotrol (Glipizide) warnings

Please, do not forget to inform your healthcare provider if you experience:

  • liver disease;
  • kidney disease;
  • chronic diarrhea or a blockage in your intestines;
  • an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
  • a disorder of your pituitary or adrenal glands;
  • a history of heart disease;
  • if you are malnourished.

Warning! Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs.

Remember the signs of low blood sugar (hypoglycemia): headache, hunger, weakness, sweating, tremors, irritability and trouble concentrating.

Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. Follow several simple roles to be safe and sound even if you have diabetes!

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