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Lamivudine Information
Lamivudine data and indications
Being ill is a sad thing, being ill with chronic or incurable disease is terrible. It takes patients a lot of time to learn how to live with major health disorders. Unfortunately, modern medicine cannot present us remedies for a number of severe health disorders such as AIDS, autoimmune diseases, cancer, hepatitis B, HIV etc. Nevertheless, patients get a perfect chance of leading painless lives with their close people due to availability of powerful medications that can suppress the most annoying symptoms and slow down the process of destruction considerably.
Lamivudine is a medication of that kind, too. It is much more powerful than the majority of other antiviral drugs and it can return patients with HBV and HIV to normal lives. Actually, Lamivudine started as a medication developed as a part of complex HIV therapy. In the course of clinical testing the substance turned out to be effecting in suppressing hepatitis B virus, too. Today Lamivudine therapy is indicated in patients with:
- Human immunodeficiency virus (HIV) at high doses as a part of complex antiviral drug therapy;
- Hepatitis B virus (HBV) with active liver imflammation at initial doses as the main therapy when all other antiviral drugs failed.
Lamivudine contraindications and warnings
No specific Lamivudine contraindications have been reported so far unless you are hypersensitive to Lamivudine or its inactive components. However, Lamivudine is reported to cause severe and even fatal cases of lactic acidosis and severe hepatomegaly with steatosis in patients taking Lamivudine alone or as a part of treatment. Despite the fact that these cases are rare, we are authorized to inform you that the majority of complications have been reported to affect women. Obesity and prolonged nucleoside exposure are considered to be risk factors for developing acidosis and severe hepatomegaly with steatosis, nevertheless several cases are known in patients with no known risk factors. Be very attentive following Lamivudine therapy - if you manage to ask for medical help in time, you will never experience severe complications.
Lamivudine therapy should not be started in pregnant and lactating women. The fact is that Lamivudine is classified as a pregnancy category C medication - it is not clear whether the drug is bound to cause harm to fetus or nursing baby but it is known that Lamivudine passes placenta and gets into breast milk effecting the baby. Ask your doctor to find a proper replacement of Lamivudine therapy!
Lamivudine is a medication with renal elimination, that is why your doctor should analyze every medication you take to avoid painful drug interactions and renal disorders.
Lamivudine doses and schedules
Please, make a point of taking your Lamivudine regularly at approximately the same time of the day. Always take your medication with a full glass of water and if your stomach is too sensitive try to take Lamivudine after a meal.
Adult patients with HBV are recommended to take 100 mg of Lamivudine once a day for a period of time of at least a year. Pediatric patients over 2 years old with HBV are recommended to take 3 mg/kg of Lamivudine once daily (up to 100 mg of the drug typical for adult patients) for a period of up to 52 weeks. Lamivudine is a relatively new medication, that is why it is impossible to say whether it is equally effective after a year's therapy. Please, come to see your doctor regularly to find out if Lamivudine is really safe and effective for you and to make sure you do not need Lamivudine dose adjustment.
HIV patients dually infected with HBV and HIV require considerably higher doses of Lamivudine to achieve desirable therapeutic effects. In such patients Lamivudine is never used alone - it is always a part of complex antiviral therapy.
Lamivudine common side effects
Do not prepare yourself for reading a long list of alarming Lamivudine side effects - this medication is really safe and this fact makes it a perfect long-term antiviral drug. If you are hypersensitive to Lamivudine or any other components of Lamivudine tablets, you can develop allergic reactions such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat - allergy is the only reason to seek immediate medical help.
The rest of Lamivudine adverse reactions are mild and rare. For instance, 24% of all Lamivudine patients can experience malaise and fatigue, fever or chills; ear, nose, and throat infections, sore throat; nausea and vomiting, abdominal discomfort and pain, diarrhea; myalgia, arthralgia; headache; skin rashes. As a rule, these symptoms arise at the very beginning of Lamivudine therapy and show that your body reacts to the new medication. They will disappear within a few days without any additional medical help.
Getting better with Lamivudine is easy - you have to follow Lamivudine schedule carefully and keep to the dose of medication prescribed by your doctor, only then you will experience positive therapeutic effect of this powerful antiviral drug.
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