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Sibutramine Information
When is Sibutramine used?
Sibutramine is a prescription medication used as an aid in weight-loss programs as an adjunct to exercise and dietary modifications. It is related to amphetamines, but its mechanism of action is quite different to that of amphetamines. While amphetamines cause additional release of serotonin, norepinephrine, Sibutramine acts on the reuptake of the same, making it a serotonin-norepinephrine reuptake inhibitor. While most other SNRIs are used as antidepressants, Sibutramine has shown no efficacy in treating depression, but it has shown much efficacy in suppressing hunger by preventing the reuptake of these chemicals, most importantly the reuptake of serotonin. It has to be noted that Sibutramine is a very potent medication and that is why it is used only in cases when it is important to have an aid in the weight-loss treatment.
Discussing Sibutramine with the healthcare provider
Sibutramine is a medication that can affect a number of different medical conditions and it is particularly dangerous for patients who are suffering from problems with their cardiovascular system. It is therefore very important that you thoroughly discuss your medical history and the state of your health at the moment before your doctor can decide if it will be safe for you to start using Sibutramine. There is a number of different medical conditions that will either prevent you from taking Sibutramine, or that will warrant special adjustments to the regimen and certain medical tests before you can start taking it. These include: depression, manias, anorexia, bulimia, allergies to the medication or any of its ingredients, high blood pressure that is not controlled, pulmonary hypertension, coronary heart disease, arrhythmias, history of heart attacks, angina, congestive heart failure, peripheral arterial occlusive disease, cerebrovascular disease, or peripheral arterial disease, closed angle glaucoma, seizure disorders, stroke, transient ischemic attack, enlarged prostate, hyperthyroidism, pheochromocytoma. It is crucial that you go over any of these with your doctor before you start taking this medication. You also need to inform your doctor in case you are already taking any other diet pills, antidepressants or MAO inhibitors. Interactions between Sibutramine and these medications can be quite severe and very dangerous.
Using Sibutramine during pregnancy
Sibutramine should not be used by pregnant women as it can have serious adverse effects to the health of the fetus. This is why you need to tell your doctor in case you are pregnant or if you become pregnant while using Sibutramine. In such a case, you will most likely be told to stop using the medication. You should also not breastfeed if you are taking Sibutramine and if you wish to breastfeed, you will need to stop taking Sibutramine, as it can pass into milk and harm the wellbeing of the nursing child.
How to properly use Sibutramine
Sibutramine should only be used as recommended by the doctor as any deviations from the prescribed regimen can only lead to adverse effects to your health and your condition. An overdose on Sibutramine can be very dangerous and this is why you should never take more of this medication than recommended. You also need to stop using the medication when your doctor instructs you to do so. You should remember that Sibutramine is just a part of the weight-loss program and that it will have little or no effect unless you are also exercising and eating properly. You should never take Sibutramine too late in the day as insomnia might occur. You will most likely be told to come in for tests covering your blood pressure and your weight. This is crucial for a beneficial and risk-free Sibutramine treatment. Sibutramine may cause dizziness and blurred vision. If this happens to you, do not drive or operate machinery until you are positive that you are feeling okay. Alcohol and other drugs that cause sedation may increase these side effects of Sibutramine.
Possible Sibutramine side effects
Sibutramine very rarely causes any serious side effects, but should you experience any of the following, make sure you inform your doctor about this at once: vomiting, unusual bleeding or bruising, tremors, swelling of the ankles, feet or legs, stomach pain, short breath, shivering, severe weakness, headache or dizziness, seizures, restlessness, one-sided weakness, numbness of the extremities, mental or mood changes, loss of consciousness, unchanging pupils, increased sweating, high fever, irregular or fast heartbeat, fainting, eye pain, excitement, disorientation, difficulties breathing, confusion, clumsiness, jaw pain, urination changes, vision changes, anxiety, agitation. Some less serious side effects are more common and these milder side effects of Sibutramine include weakness, upset stomach, sore throat, insomnia, runny nose, painful menstruations, nervousness, nausea, joint pain, changes in appetite, headaches, dry mouth, dizziness, constipation and back pain.
Medications that might interact with Sibutramine
Among the medications that might interact with Sibutramine, you will find: dextromethorphan, imidazole antifungals, dihydroergotamine, MAOIs, lithium, narcotics, pentazocine, SSRIs, tryptophan, ephedrine, anticoagulants and cyclosporine.
In case of a Sibutramine overdose
In case you suspect a Sibutramine overdose, seek emergency medical help. You might experience irregular or fast heartbeat, persistent or severe headache or dizziness.